Michael, 

Obviously paying off a loan or debt quicker than the contractual time-frame gets you out of debt quicker.

In the example of a mortgage: as mortgage interest is tax-deductible, you would need to weigh the benefits of still having the mortgage and the interest against the tax benefits to you.  This can be different for everyone depending on their tax situation; so best to consult an accountant or tax professional as to if paying off a mortgage, or a tax deductible interest type loan is a benefit.

Others here may have some other ideas and suggestions as well.

Regards, 

Jon